Background and objectives: Urinary tract infections carry a high risk of recurrence and antibiotic resistance due to biofilm formation. This study aims to identify the common bacterial pathogen responsible for UTI in Erbil setting and identify their pathogenic characteristics and sensitivity to commonly used antibiotics, using the minimal inhibitory concentration (MIC) method.
Methods: 96-flat wells microtiter plate was used for detection of the degree of biofilm formation of E. coli strains isolated from patients with urinary tract infection. Standard breakpoint MIC have been compared with MIC results of antibiotics
Results: Only 5.6% of total samples showed UTI, the most common bacterial isolate was E. coli (43.2%). Around 26% of pyuric cases appeared to be of sterile type. The biofilm formation involved 9.4% strong adhesion. Around 50% of isolates showed beta hemolysis. The most sensitive antibiotics include nitrofurantine (81.3%), gatifluxacin (40.6%) and Ciprofloxacine (37.5%).
Conclusion: Most common pathogens in UTI are E.coli. There was no correlation between biofilm formation and the presence of any of the other virulence factor such as antibiotic resistants and hemolysis. The more effective antibiotics against E.coli in this setting are gatifluxacine, Ciprofloxacin and nitrfuratoin having most MIC fall close to their standard breakpoints.
Keywords: Antibiotic, biofilm, hemolysis, UTI.
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Background and Objectives: The importance of precordial ST-segment depression in patients with early inferior ST-segment elevation myocardial infarction remain unclear. Many studies have reported that patients with precordial ST-segment depression appear to have large infarctions.
The objectives of this study was to evaluate the effect of precordial ST-segment depression in patients with early inferior ST-segment elevation myocardial infarction on the left ventricular systolic function and left ventricular regional wall abnormalities.
Patients & Methods: Fifty eight patients with first inferior ST-segments elevation myocardial infarction (37 male, 21 female), their ages ranged from 30-91year,mean age 60.59±11.21 who underwent thrombolysis in the Coronary Care Unit of Erbil Teaching Hospital for the period from August 2008 to August 2009 were included in this study. Two-dimensional echocardiography was performed in the first week of acute inferior myocardial infarction. Patients were classified according to the absence (group I, 30 ,51.72%) or presence (group II ,28 , 48.28%) of precordial ST- segment depression .
Results: Group-II patients had a higher significant incidence of left ventricular systolic dysfunction (8,28.57%) than group I (2,6.67%),P=0.027 ,despite thrombolytic therapy (alteplase). Group-II patients had higher significant incidence of left ventricular regional wall abnormalities ( 12,42.9%) than group-I (3,10%),P 0.00 ,despite thrombolytic therapy (alteplase).
Conclusions: Early two-dimensional echocardiography is recommended for patients with inferior ST-segment elevation myocardial infarction associated with precordial ST-segment depression for the earliest detection of regional wall abnormalities and left ventricular systolic dysfunction.
Keywords: Left ventricular systolic function.
Background and objective: Stroke is a worldwide health problem. This study was carried out to find out the risk factors associated with stroke in Erbil city.
Methods: A hospital based case-control study was carried out in Erbil city from January, 1st 2009 to June, 30th 2009. The sample included (173 cases and 173 controls) cases admitted to Erbil teaching hospitals with first-ever stroke diagnosed by the consultant internist or neurologists and confirmed by brain CT-scan. Sex and age-matched (� 5 years) patients admitted to the same hospital, who do not have stroke, were taken as a control group.
Results: The mean � SD ages of cases and controls were 62.2 �13.4 and 61.54 �13.16 years, respectively with a male: female ratio of 1.1:1. Nearly 70% were ischaemic and 30% were haemorrhagic. A slightly more than half (51.45%) of strokes occurred in the 7th and 8th decades of life. Multiple logistic regression analysis revealed statistically significant association between smoking (P<0.001), exercise (P<0.001), hypertension (P=0.001), family history of stroke (P=0.004), BMI (P=0.012) and PCV% (P<0.001) with stroke. However multiple logistic regressions of risk factors for ischaemic and haemorrhag